5-Amino-1MQ is a selective inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme that plays a role in cellular methylation and energy metabolism. It's a relatively newer entry in the metabolic research space, but one that's attracted considerable attention from researchers studying how NNMT activity connects to broader metabolic function at the cellular level.

Research has explored how NNMT inhibition with compounds like 5-Amino-1MQ affects NAD+ availability and methylation balance within cells. Since NNMT consumes methyl groups during its activity, inhibiting it may influence the pool of available methylation substrates — a dynamic that researchers study in the context of cellular signaling and energy regulation.

Studies have investigated 5-Amino-1MQ in pre-clinical metabolic research models, looking at how NNMT inhibition interacts with adipocyte biology and energy homeostasis pathways. It's considered a useful research tool for labs working on methylation biochemistry and metabolic pathway analysis.

myPEPT supplies 5-Amino-1MQ at ≥99% verified purity, with a Certificate of Analysis (COA) from independent third-party testing. All batches are research-grade and shipped across the EU with appropriate packaging for laboratory use.

What researchers should know: 5-Amino-1MQ is supplied strictly for laboratory research use. It is not approved for human consumption and is not a medicinal product. Handle and store according to your institution's protocols and all applicable local regulations.