Semax is a synthetic heptapeptide analog of the adrenocorticotropic hormone (ACTH) fragment ACTH(4-7), developed at the Institute of Molecular Genetics in Moscow. It has been studied in neuroscience research for its apparent neurotrophin-like activity — particularly its interaction with BDNF (brain-derived neurotrophic factor) and TrkB receptor signaling, pathways that are central to neuronal survival and synaptic plasticity research.

Research has explored Semax in models of neuroprotection and cognitive signaling, investigating how ACTH-derived peptides interact with central nervous system biochemistry. Studies have examined its influence on dopaminergic and serotonergic neurotransmission, as well as its potential role in modulating the HPA (hypothalamic-pituitary-adrenal) axis response in pre-clinical models.

Semax has also been investigated in models examining cerebrovascular biology and neuroinflammation, where BDNF-related signaling plays a documented role in neuronal recovery pathways. Its ACTH analog structure makes it a useful research tool for labs studying neuropeptide pharmacology and central nervous system peptide signaling.

myPEPT supplies Semax at ≥99% verified purity with a Certificate of Analysis from independent lab testing. Lyophilized and shipped across the EU in research-grade packaging.

What researchers should know: Semax is a research peptide for laboratory use only. It is not approved as a therapeutic or nootropic supplement for human use in most jurisdictions. Always handle in accordance with your institution's neuroscience compound protocols and applicable local regulations.